Neurotransmitter Table
| Neuro
transmitter |
Receptor
Subtype |
Location/Function/Effects/symptoms of excess or deficit if applicable | Distribution
(ie: CNS/PNS, GI, vascular) |
Drug classes that target this neurotransmitter or receptor | Specific medications that target this neurotransmitter or receptor |
| Glutamate | AMPA | ||||
| NMDA | |||||
| GABA | GABA a | ||||
| GABA b | |||||
| Serotonin
5HT |
5HT 1a | ||||
| 5HT 1B
|
|||||
| 5HT 1d | |||||
| 5HT 1E
|
|||||
| 5HT 1F | |||||
| 5HT 2A | |||||
| 5HT2B
|
|||||
| 5HT 2C | |||||
| 5HT 3 | Ligand gated ion channels. highest levels in the brain stem-
Targets: decreases nausea/emesis
Will inhibit the release of NE and Ach- Targets: cognition, anxiety, addiction. |
CNS
(chemoreceptor trigger zone) PNS: GI tract (vagal nerve) |
Antiemetics
Antidepressants
|
Antiemetics:
ondansetron, granisetron, dolasetron, palonosetron
Antidepressants: Mirtazapine vortioxetine |
|
| 5HT 4 | |||||
| 5HT 5 AB | |||||
| 5HT6 | |||||
| 5HT 7 | |||||
| NE
norepinephrine |
α 1 | ||||
| α 2 | |||||
| DA
Dopamine |
D1 | ||||
| D2 | |||||
| D3 | |||||
| D4 | |||||
| Ach
Acetylcholine |
Muscarinic | ||||
| Nicotinic | |||||
| Histamine | |||||
| Melatonin |
1. For each neurotransmitter and receptor type, complete the following columns:
a. Location/function/effects/symptoms of excess or deficit
b. Distribution
c. Drug classes that target this neurotransmitter or receptor
d. All neurotransmitters and receptor types: Specific medications that target this neurotransmitter or receptor
2. This criterion is linked to a Learning Outcome Organization
3. Font is consistent throughout table, and grammar, spelling, and/or punctuation are accurate.
A total of 4 references needed with intext citation. 2 references provided below. Please use 7th edition APA scholarly references that are witin 5 years.
Stahl, S.M. (2020). Stahl’s essential psychopharmacology: Prescribers guide (7th ed.). Cambridge University Press.
Stahl, S. M. (2021). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (5th ed.). Cambridge University Press.
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